DNA as a guide to prevent health problems

Written by Dirk Jan Buter on September 07, 2024. Photo by Dirk Jan Buter. Created with a collaborative synthesis of artificial and human intelligence. Join Dirk Jan Buter's Aspiring Innovators Magazine to support our work and enable us to keep creating meaningful content.

I had wanted to have my DNA tested for a long time to learn more about my genetic mutations and ancestry. In this way, I wanted to discover the weaknesses in my DNA profile and take preventive measures. That is why I had my DNA tested via 23andMe.

I was full of anticipation and curiosity as I waited for the results. What if I had a mutation that could affect my life? What if I had a condition that I did not know I had? My tests yielded several results that caught my attention. We will discuss these in detail below. But first, a brief introduction to 23andMe.

23andMe

23andMe is a genetic testing service that gives users detailed insights into their genetic makeup. The service includes reports on ancestry, traits, and, most crucially, health predictions. The health reports analyze specific genetic variants that are associated with various conditions. From common diseases like type 2 diabetes and cardiovascular disease to rare genetic conditions.

At 23andMe, they test with a simple saliva sample. This sample is characterized using genotyping, in which specifically selected parts of the DNA are analyzed with a specially developed DNA chip. So, the entire DNA is not tested, but specific genetic markers are examined to create a profile.

Results

The most surprising revelation was that I have more Neanderthal DNA than others. This unexpected discovery put a humorous twist on the serious business of genetic testing. My origins were also a particular result: I am a true Dutchman according to my DNA, although people often ask if I have a foreign background.

The information about my mutations and possible future conditions was excellent. Only one significant finding emerged: a genetic predisposition to diabetes. Other mutations found in my DNA are related to conditions that I have a minimal chance of developing.

Preventing Diabetes

Now, armed with this knowledge, I feel a sense of relief. So that was not so bad at all! Now, I can take proactive steps to prevent diabetes. While I can’t say I’m a big fan of exercise, it’s clear that it’s crucial to my health. This new insight is a powerful motivator for being more health conscious.

I looked up what I should do to prevent type 2 diabetes:

  • Adopt a healthy lifestyle and eat a balanced diet with fiber, vegetables, and fruits.
  • Limit sugary and processed foods.
  • Exercise regularly; at least 30 minutes of moderate exercise per day.
  • Maintain a healthy weight and avoid being overweight.
  • Limit alcohol consumption and don’t smoke.
  • Check your blood sugar regularly, especially if you have a family history of diabetes.
  • Reduce stress by using relaxation techniques such as meditation or yoga.
  • Get enough sleep, as lack of sleep can increase your risk of diabetes.
  • See a doctor for regular checkups and discuss any concerns you may have about your risk of diabetes.

Analyzing the data

The information on 23andMe is just a sample of all the results. It is possible to gain even more insights by downloading the raw data. I understand that sharing raw genetic data carries potential risks for privacy and misuse. That is why I have decided not to make my data available here. If you are going to test your DNA, you can compare the raw data with different genes of other genetic diseases or conditions on the web. An example is this site: https://www.snpedia.com/

Experience

My experiences with 23andMe have been generally positive. Waiting for the results requires patience, but the excitement and insights you eventually receive make it worth it. For example, being able to identify an increased risk of diabetes allows me to take preventive measures.

Conclusion

It would be suitable for everyone to consider having their DNA tested seriously. This can prevent future misery and help them adapt their lifestyle to their unique genetic makeup. Testing my DNA makes me wiser and more aware of my genetic risks. This helps me to live healthier. Because prevention is better than cure.